Retrospective case-case study investigation of a significant increase in <i>Cryptosporidium</i> spp. in England and Wales, August to September 2023.

ABSTRACT: BackgroundLaboratory surveillance detected an unprecedented increase in Cryptosporidium spp. (predominantly Cryptosporidium hominis) in England and Wales in August 2023. Cases are not routinely followed up in all of England and Wales, and initial investigations identified no common exposures.AimTo perform a retrospective case-case study investigation of the increase in Cryptosporidium spp. in England and Wales.MethodsWe conducted an unmatched case-case study with 203 cases of laboratory-confirmed C. hominis and 614 comparator cases of laboratory-confirmed Campylobacter spp. reported between 14 August and 30 September 2023. We fitted a multilevel logistic regression model, with random intercepts for geographical region, to estimate adjusted odds ratios (aO

SUBMITTER: Williams SV 

PROVIDER: S-EPMC11887033 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature