Global, regional, and national mortality of larynx cancer from 1990 to 2021: results from the global burden of disease study.

ABSTRACT:

Background

Larynx cancer, a major upper respiratory tract malignancy, remains a global public health challenge, driven by smoking, alcohol use, and chronic inflammation, despite medical and public health advancements.

Methods

Data from the Global Burden of Disease 2021 study were used to assess larynx cancer mortality trends from 1990 to 2021 across global, regional, and national levels. Death rates, absolute mortality numbers, and Estimated Annual Percentage Change (EAPC) were calculated.

Results

Globally, the number of deaths from larynx cancer increased by 36.67% between 1990 and 2021, while death rates slightly declined, with an EAPC of -0.41. Males consistently accounted for the majority of deaths, with 100,393 deaths in 2021, though female mortality showed a lar

SUBMITTER: Han D 

PROVIDER: S-EPMC11887237 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature