Analysis of early risk factors of death in preterm infants treated with iNO: a national multicentre retrospective study.

ABSTRACT:

Objective

To analyse early risk factors for mortality in preterm infants treated with inhaled nitric oxide (iNO) in China.

Design

A retrospective observational case-control study.

Setting

8 tertiary hospitals in 5 regions of China.

Patients

726 preterm infants treated with iNO for hypoxic respiratory failure or persistent pulmonary hypertension of newborns.

Interventions

None.

Measurements

The primary outcome was survival status at discharge.

Main results

(1) The mortality rate was 27.1% (197/726), and which significantly reduced with increasing gestational age (GA) and birth weight. (2) Compared with the survival group, the death group had significantly greater use of assisted reproductive technology, higher multiple pregnancy rates and lo

SUBMITTER: Gao L 

PROVIDER: S-EPMC11887303 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature