Intracortical microstimulation of human somatosensory cortex induces natural perceptual biases.

ABSTRACT: Time-order error, a psychophysical phenomenon in which the duration in between successive stimuli alters perception, has been studied for decades by neuroscientists and psychologists. To date, however, the locus of these effects is unknown. We use intracortical microstimulation of somatosensory cortex in three humans with spinal cord injury as a tool to bypass initial stages of processing and restrict the possible locations that signals could be modified. Using a 2-interval forced choice amplitude discrimination paradigm, we first assessed the extent to which order effects are observed. Comparing trials where the standard stimulus was in the first or second interval, we found that systematic biases are exhibited, typically causing the intensity of the second stimulus to be overestimated Th

SUBMITTER: Greenspon CM 

PROVIDER: S-EPMC11887563 | biostudies-literature | 2024 Nov-Dec

REPOSITORIES: biostudies-literature