Subjective salience ratings are a reliable proxy for physiological measures of arousal.

ABSTRACT: Pain is an inherently salient multidimensional experience that signals potential bodily threats and promotes nocifensive behaviours. Any stimulus can be salient depending on its features and context. This poses a challenge in delineating pain-specific processes in the brain, rather than salience-driven activity. It is thus essential to salience match control (innocuous) stimuli and noxious stimuli, to remove salience effects, when aiming to delineate pain-specific mechanisms. Previous studies have salience-matched either through subjective salience ratings or the skin conductance response (SCR). The construct of salience is not intuitive, and thus matching through self-report poses challenges. SCR is used as a proxy measure that captures physiological arousal, which overcomes the nebulous

SUBMITTER: Hadjis GE 

PROVIDER: S-EPMC11888199 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature