Multiple methods for assessing learning and memory in <i>Drosophila melanogaster</i> demonstrates the highly complex, context-dependent genetic underpinnings of cognitive traits.

ABSTRACT: Learning and memory are fundamental for an individual to be able to respond to changing stimuli in their environment. Between individuals we see variation in their ability to perform learning and memory tasks, however, it is still largely unknown what genetic factors may impact this variability. To gain better insight to the genetic components impacting variation in learning and memory, we use recombinant inbred lines (RILs) from the Drosophila synthetic population resource (DSPR), a multiparent mapping population exhibiting natural variation in many traits. Using a reward based associative learning and memory assay, we trained flies to associate an odor with a sucrose reward under starvation condition and measured olfactory learning and memory ability in y-mazes for 50 DSPR RILs. W

SUBMITTER: Hamlin V 

PROVIDER: S-EPMC11888412 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature