A deep insight into the sialome of the house fly, Musca domestica, infected with the salivary gland hypertrophy virus (MdSGHV).

ABSTRACT: The house fly, Musca domestica, serves as a mechanical vector for numerous pathogens, posing a significant risk to human and animal health. More than two decades ago, the Musca domestica salivary gland hypertrophy virus (MdSGHV) was discovered, infecting both males and females flies and disrupting mating and the reproductive process. While MdSGHV can infect various tissues, its primary replication site is the house fly salivary gland. It is well established that arthropod salivary glands play an important role not only in acquiring food but also in transmitting pathogens. Therefore, understanding the composition of vector salivary glands and the interactions between vector and pathogen components is essential for developing future control strategies. To this end, we conducted a comprehensi

SUBMITTER: Lu S 

PROVIDER: S-EPMC11889141 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature