The structural covariance of reading-related brain regions in adults and children with typical or poor reading skills.

ABSTRACT: Structural covariance (SC) is a promising approach for studying brain organization in the context of literacy and developmental disorders, offering insights into both structural and functional underpinnings and potential experience-dependent co-development of functional brain networks. Here, we explore the influence of maturation and reading skill on SC in reading-related brain regions. Whole-brain SC analyses were conducted for six key regions of the reading network, including an anterior and posterior subdivision of the visual word form area (VWFA). To study maturational effects, SC was compared between typical-reading adults (N = 134, 25.3 ± 4 yrs) and children (N = 110, 9.6 ± 1.6 yrs). The impact of reading skills on SC was assessed by comparing typical-reading children (N = 110, 9.6 ±

SUBMITTER: Haugg A 

PROVIDER: S-EPMC11889628 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature