The contribution of childhood trauma to irritability symptoms.

ABSTRACT:

Background

Irritability is a transdiagnostic psychiatric phenotype defined as an increased proneness to anger relative to peers. Trauma is defined as actual or threatened death, serious injury, or sexual violence while adversity more broadly describes difficult or challenging situations including abuse, neglect, and household dysfunction. Irritability [or aggression] is symptom of posttraumatic stress disorder (PTSD) and may arise in response to trauma or traumatic events. Responses to negative early life experiences may differ based on the type of exposure, for example, threat (abuse) versus deprivation (neglect), with implications for development of psychopathology. Therefore, the objective of this study was to investigate the relation between exposure to threat and deprivation,

SUBMITTER: Grasser LR 

PROVIDER: S-EPMC11889654 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature