Analysis of zinc and copper levels in very low birth weight infants using human milk additives: phase 1 trial findings.

ABSTRACT:

Objective

The aim of this study was to assess whether the micronutrients zinc and copper, provided by human milk additives, are sufficient for very low birth weight preterm infants.

Method

A phase 1 randomized double-blind controlled trial was conducted with very low birth weight preterm infants. This is a secondary analysis of copper and zinc. Sixty-six newborns were part of the initial sample, with forty participating and reaching the final stage of the study. Inclusion criteria were: gestational age less than 37 weeks, birth weight greater than or equal to 750 g and less than or equal to 1500 g, small or appropriate for gestational age, exclusively receiving human milk at a volume greater than or equal to 100 mL per kilogram per day, and hemodynamically stable. Participan

SUBMITTER: Oliveira RG 

PROVIDER: S-EPMC11889681 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature