Growth charts of Brazilian girls with Turner syndrome without the use of GH or oxandrolone.

ABSTRACT:

Objective

The development of specific growth charts for Turner Syndrome (TS) promotes adequate assessment of growth and weight gain, and earlier diagnosis of comorbidities, and may help to analyze the effectiveness of treatments to promote growth and puberty. The aim of this study was to construct a growth chart with the largest possible series of patients with a cytogenetic diagnosis of TS from a Brazilian reference center.

Methods

This is a longitudinal study, with 259 cases of TS born between 1957 and 2014 and followed between 1975 and 2019, without the use of GH or oxandrolone. 3,160 height measurements and 2,918 wt measurements were used, with subsequent calculation of the Body Mass Index (BMI). For data analysis, the "GAMLSS" package of the "R" software was used.

Re

SUBMITTER: Carpini-Dantas S 

PROVIDER: S-EPMC11889696 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature