Prevalence and clinical characteristics of patients with hsCRP testing and test-confirmed systemic inflammation among individuals with atherosclerotic cardiovascular disease with or without chronic kidney disease in the United States (PLUTUS).

ABSTRACT:

Background

Systemic inflammation (SI) is a risk factor for atherosclerotic cardiovascular disease (ASCVD) and is most commonly assessed by measuring levels of high-sensitivity C-reactive protein (hsCRP).

Objective

This study aimed to determine hsCRP testing rates and SI prevalence in patients with ASCVD and in a subset of patients with chronic kidney disease (CKD).

Methods

This was a retrospective, cross-sectional analysis using US-based data from the Optum® de-identified Electronic Health Record data set (Optum® EHR; 1/1/2017-12/31/2021). hsCRP testing rates and SI prevalence (hsCRP ≥2 to <10 mg/L) were evaluated by calendar year. Demographics, comorbidities, and treatment patterns were compared between patients with ASCVD, ASCVD + CKD, and ASCVD + stage 3/4 CKD, wit

SUBMITTER: Lv L 

PROVIDER: S-EPMC11889733 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature