Determinative sleep traits associated with dyslipidemia in obstructive sleep apnea patients.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is recognized to increase the risk of dyslipidemia; however, the specific sleep traits in OSA that influence dyslipidemia are poorly understood. This study sought to determine which sleep traits are independently associated with dyslipidemia and serum lipid profiles in patients with OSA.

Methods

In this cohort study, 5239 participants were included from the Sleep Heart Health Study. Further, OSA was diagnosed via polysomnography with an AHI ≥ 5 events/h. Sleep traits were assessed using polysomnographic data and questionnaires. Then, logistic regression was used to identify sleep traits that predict dyslipidemia in OSA patients. Non-linear associations between sleep traits and dyslipidemia were evaluated using restricted cubic splines

SUBMITTER: Wang L 

PROVIDER: S-EPMC11889753 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature