Effects of transcranial direct current stimulation combined with retrieval practice on semantic memory in patients with schizophrenia.

ABSTRACT:

Background

The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial direct current stimulation (tDCS) and retrieval practice have been demonstrated as external techniques capable of ameliorating the semantic processing deficit in individuals with schizophrenia. The inquiry examines whether the combined effect of tDCS and retrieval practice, following tDCS intervention targeting the left dorsolateral prefrontal cortex (L-DLPFC) in patients with schizophrenia, contributes to the preservation of semantic memory in these individuals.

Methods

We recruited 52 patients diagnosed with schizophrenia from hospitals. After five consecutive days of tDCS intervention (2 mA × 20 mins, twice per day), we administered a word

SUBMITTER: Pan W 

PROVIDER: S-EPMC11889829 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature