Rumen microbiome associates with postpartum ketosis development in dairy cows: a prospective nested case-control study.

ABSTRACT:

Background

Approximately, one-third of dairy cows suffer from postpartum diseases. Ketosis is considered an important inducer of other postpartum diseases by disrupting energy metabolism. Although the rumen microbiome may be involved in the etiology of ketosis by supplying volatile fatty acids, the rumen environmental dynamics of ketosis cows are unclear. Using multi-omics, this study aimed to elucidate changes in the rumen microbiome during parturition of ketosis cows and the association between the rumen microbiome and host energy metabolism. The study included 810 rumen content samples and 789 serum samples from day - 21 and 21 relative to calving day from 61 ketosis cows and 84 healthy cows.

Results

In ketosis cows, the rumen bacterial composition after parturition chang

SUBMITTER: Kong F 

PROVIDER: S-EPMC11889851 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature