Evaluation of C-reactive protein levels in patients with penile cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

C-reactive protein (CRP) is an essential biomarker for evaluating penile cancer prognosis. Previous studies have reported conflicting outcomes concerning the correlation between CRP levels and penile cancer prognosis. This study aimed to investigate this relationship by conducting a meta-analysis of published literature.

Methods

A systematic literature search was conducted using the Cochrane Library, PubMed, and Embase databases to analyze the prognostic significance of serum CRP levels in individuals diagnosed with penile cancer. Pooled risk estimates were calculated using fixed-effects or random-effects models, depending on the degree of interstudy heterogeneity.

Results

Sixty-eight articles were reviewed, identifying 8 articles and 989 patients that met

SUBMITTER: Qin T 

PROVIDER: S-EPMC11889917 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature