Transcriptomic analysis of broiler chickens reveals metabolic adaptations to a reduced crude protein diet.

ABSTRACT: Protein is an essential component of poultry diets and directly influences growth performance, profitability, and the environment. While the relationship between animal performance and nutrient intake is modulated by gene expression, the transcriptomic mechanisms underlying broiler adaptation to varying dietary protein levels remain underexplored. This research investigated the liver transcriptomic response of broiler chickens fed a reduced crude protein (RCP) diet, aiming to identify differentially expressed genes (DEGs) and metabolic pathways that may underlie protein metabolism and growth. A total of 256 as-hatched Cobb 500 broilers were fed standard starter and grower diets. At the finisher stage (days 19-28), birds were randomly assigned to one of two treatments: normal crude protein

SUBMITTER: Asiamah CA 

PROVIDER: S-EPMC11889961 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature