Tinidazole vs metronidazole for the treatment of bacterial vaginosis: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Tinidazole shows potential as a first-line treatment for bacterial vaginosis (BV). However, its superiority to metronidazole remains uncertain. Therefore, this meta-analysis compares tinidazole versus metronidazole in patients with BV.

Methods

We systematically searched PubMed, Embase and Cochrane for studies comparing tinidazole and metronidazole in patients with BV. Statistical analyses were performed using R Studio 4.3.2. Heterogeneity was examined with the Cochran Q test and I² statistics. Risk ratios (RR) with 95% confidence intervals (CI) were pooled across trials. Outcomes of interest were BV cure at the first and the second follow-up appointment, and adverse events such as nausea and bad or metallic taste.

Results

Five randomized contro

SUBMITTER: Sobral MVS 

PROVIDER: S-EPMC11890333 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature