Neutrophils are involved in the development and outcomes of plastic bronchitis associated with Mycoplasma pneumoniae pneumonia.

ABSTRACT:

Background

Previous research has demonstrated a notable increase in neutrophil counts among pediatric patients with plastic bronchitis (PB) associated with Mycoplasma pneumoniae pneumonia (MPP). However, the role of neutrophils in MPP-associated PB remains largely elusive.

Methods

This is a nested case-control study that enrolled patients diagnosed with MPP who underwent bronchoscopy in our department during the MPP pandemic from September 2023 to January 2024. We conducted an analysis of clinical characteristics, blood samples, bronchoalveolar lavage fluid (BALF), and cast specimens, correlating these factors with the development and outcomes of PB.

Results

Among the 557 patients with MPP included in the study, 21 (3.8%) developed PB. The peripheral neutrophil count

SUBMITTER: Huang X 

PROVIDER: S-EPMC11890523 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature