Vaginal probiotics as therapeutic adjuncts for improving embryo transfer success rates: a systematic review and meta-analysis.

ABSTRACT:

Background

Infertility treatments are continually evolving, with vaginal probiotic supplementation before embryo transfer (ET) being explored as a potential method to improve clinical outcomes. So, this systematic review evaluated the effect of vaginal probiotics on pregnancy rates following ET.

Methods

Studies were identified through PubMed, Scopus, Web of Science, Cochrane, and clinical trial registries up to October 17, 2024. We included prospective interventional studies (RCTs or quasi-experimental) focusing on pregnancy outcomes post-ET. We excluded non-prospective studies, non-vaginal routes of probiotic administration, and studies with insufficient methodological or statistical details. The data was extracted from each qualifying study by two reviewers and recorded us

SUBMITTER: Maleki-Hajiagha A 

PROVIDER: S-EPMC11890537 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature