Sex-specific trends in the global burden and risk factors of atrial fibrillation and flutter from 1990 to 2021.

ABSTRACT: Significant sex disparities exist in the burden of atrial fibrillation and flutter. However, comprehensive and systematic analysis of its global trend by sex is scarce. The Global Burden of Disease Study 2021 was used as data source for analysis. Sex-specific prevalence, incidence, disability-adjusted life years (DALY), and mortality rates per 100,000 population from atrial fibrillation and flutter were estimated using the Bayesian meta-regression method. Temporal trends of average annual percent change (AAPC) of age-standardized and age-specific burdens across age bands were evaluated using the joinpoint model stratified by socio-demographic index (SDI). Sex differences in trends were tested using pairwise comparison. From 1990 to 2021, the global age-standardized DALY rate [from 109.93 (

SUBMITTER: Peng X 

PROVIDER: S-EPMC11890608 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature