The structure of depressive symptoms and characteristics and their relation to overall severity in major depressive disorder.

ABSTRACT: Although many investigators have examined symptoms of major depressive disorder (MDD), the multivariate relations among these features of depression and their relative associations with overall severity of depression are not well understood. The present study is the first to examine the underlying factor structure of depression across a broad set of constructs and to model the multivariate association of these factors with the overall severity of depression. We conducted a large-scale factor analysis and multiple regression in a sample of participants diagnosed with MDD (N = 233) and healthy controls (N = 235). We obtained a five-factor solution composed of the following factors: (1) anxiety; (2) behavioral activation; (3) core symptoms; (4) rumination; and (5) emotional intensity. The cor

SUBMITTER: Miller CH 

PROVIDER: S-EPMC11890707 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature