Shuhe granule for insomnia: study protocol for a double-blind, randomized, placebo-controlled trial.

ABSTRACT:

Introduction

Modern medical treatment of insomnia is often associated with issues like addiction, drug resistance, and a high risk of relapse post drug withdrawal. To tackle these challenges, the Chinese medicine formula Shuhe granule (SHG) has been employed in insomnia treatment at Guangdong Provincial Hospital of Chinese Medicine. Despite this, there is currently a lack of reliable evidence from evidence-based trials to support the widespread use of SHG in insomnia treatment. Therefore, we have developed a randomized controlled trial to assess the efficacy and safety of SHG in insomnia treatment.

Method

This study will be a single-center, double-blind, randomized, parallel group, placebo-controlled clinical trial involving a total of 160 eligible patients aged between 18 a

SUBMITTER: Gao Y 

PROVIDER: S-EPMC11891157 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature