Gut microbiome differences in individuals with PTSD compared to trauma-exposed controls: a systematic review.

ABSTRACT: Post-traumatic stress disorder (PTSD) is a common mental health disorder that can occur following exposure to a traumatic event, and is characterized by symptoms including intrusive memories, dissociation, and nightmares. PTSD poses significant suffering on the individual and can reduce quality of life substantially, however, its mechanisms are not fully understood. It has also been associated with gut abnormalities, such as with irritable bowel syndrome, indicating possible involvement of the gut microbiome and gut-brain axis. Whereas previous research has implicated the gut microbiome and microbiome gut-brain axis in various mental health disorders, the relationship between gut microbiome function and PTSD is unclear. Specifically, little is known about whether specific gut microbiome co

SUBMITTER: Winder C 

PROVIDER: S-EPMC11891237 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature