The triglyceride-glucose index is associated with a higher risk of hypertension: evidence from a cross-sectional study of Chinese adults and meta-analysis of epidemiology studies.

ABSTRACT:

Background

The results of population-based studies show a diverse association between the triglyceride-glucose (TyG) index and hypertension. The present study aimed to investigate this association based on a cross-sectional study on Chinese adults and meta-analysis of epidemiology studies.

Methods

The cross-sectional analysis used the baseline data from the on-going REACTION study in China. The TyG index was calculated as Ln [triglyceride(mg/dl)×fasting plasma glucose(mg/dl)/2]. A multivariate-adjusted logistic regression model was used to calculate the odds ratio (OR) with a 95% confidence interval (CIs) for the prevalence of hypertension, with the lowest TyG quartile as a reference.

Results

A total of 4,177 participants aged 58.62 ± 8.40 years were included. TyG was

SUBMITTER: Ren X 

PROVIDER: S-EPMC11891255 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature