Agent Orange and head and neck cancer: A systematic review and meta-analysis.

ABSTRACT:

Objective

To assess the incidence of head and neck cancer in patients exposed to Agent Orange and related dioxins.

Methods

Studies were identified through CINAHL, PubMed, and Scopus. Primary studies were identified through April 2023. Articles were included reporting incidence of head and neck cancer and/or deaths due to head and neck cancer in participants exposed to Agent Orange. Meta-analysis of proportions was conducted to calculate incidence and mortality by primary site in those who were exposed to Agent Orange and for control groups. A comparison of proportions was used to compare rates in exposed and control groups.

Results

Of 1530 unique abstracts screened, 13 studies were included in the systematic review. Of the exposed patients with reported subsites, oral

SUBMITTER: Monaghan NP 

PROVIDER: S-EPMC11891274 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature