Exploring functional connectivity in clinical and data-driven groups of preterm and term adults.

ABSTRACT: Adults born very preterm (i.e. at <33 weeks' gestation) are more susceptible to long-lasting structural and functional brain alterations and cognitive and socio-emotional difficulties, compared with full-term controls. However, behavioural heterogeneity within very preterm and full-term individuals makes it challenging to find biomarkers of specific outcomes. To address these questions, we parsed brain-behaviour heterogeneity in participants subdivided according to their clinical birth status (very preterm versus full term) and/or data-driven behavioural phenotype (regardless of birth status). Participants were followed-up in adulthood (median age 30 years) as part of a wider longitudinal case-control cohort study. The Network Based Statistic approach was used to identify topological compo

SUBMITTER: Hadaya L 

PROVIDER: S-EPMC11891483 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature