Does Adiponectin Inform Cardiovascular Risk in Older Adults?: The ARIC Study.

ABSTRACT:

Background

Adiponectin, an atheroprotective adipokine, is associated with adverse outcomes in older age. It is unclear whether this is due to overlapping pathophysiological pathways with N-terminal pro-B-type natriuretic peptide (NT-proBNP).

Objectives

The authors investigated adiponectin's associations with cardiovascular disease (CVD) risk in older adults.

Methods

Among Atherosclerosis Risk in Communities prospective cohort study participants without baseline CVD at visit 5 (n = 4,729, mean age 75), adiponectin and adiponectin/NT-proBNP category associations with incident CVD events (heart failure [HF], atherosclerotic cardiovascular disease, and death during median follow-up of 5.5 years) and echocardiographic parameters were assessed. Metabolomic signatures of adi

SUBMITTER: Abushamat LA 

PROVIDER: S-EPMC11891717 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature