Microfluidic 3D Bioprinting of Foamed Fibers with Controlled Micromorphology.

ABSTRACT: The synergistic integration of microfluidic technologies with additive manufacturing systems is advancing the development of innovative platforms to 3D bioprint scaffolds for tissue engineering with unparalleled biological relevance. Significant interest is growing in realizing porous functionally graded materials (pFGMs) that can resemble the hierarchical organization of porosity found in bone tissue. This study introduces a method for fabricating porous scaffolds based on the real-time generation of a liquid foam, which is gelled, forming porous fibers that are organized into structured matrixes using a 3D bioprinting system. The primary advantage of this approach is the possibility to adjust bubble size during printing dynamically, modifying the characteristics of the deposited foamed f

SUBMITTER: Serpe F 

PROVIDER: S-EPMC11891826 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature