Native state structural and chemical characterisation of Pickering emulsions: A cryo-electron microscopy study.

ABSTRACT: Transmission electron microscopy can be used for the characterisation of a wide range of thin specimens, but soft matter and aqueous samples such as gels, nanoparticle dispersions, and emulsions will dry out and collapse under the microscope vacuum, therefore losing information on their native state and ultimately limiting the understanding of the sample. This study examines commonly used techniques in transmission electron microscopy when applied to the characterisation of cryogenically frozen Pickering emulsion samples. Oil-in-water Pickering emulsions stabilised by 3 to 5 nm platinum nanoparticles were cryogenically frozen by plunge-freezing into liquid ethane to retain the native structure of the system without inducing crystallisation of the droplet oil cores. A comparison between the

SUBMITTER: Fernandez Ainaga DL 

PROVIDER: S-EPMC11891983 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature