Prevalence of <i>Bordetella pertussis</i> among children aged 4 years and above presenting with acute respiratory tract infection: a cross-sectional study.

ABSTRACT:

Introduction and aim

In Malaysia, pertussis in children beyond infancy is underreported. This study aimed to determine the prevalence of Bordetella pertussis and the prevalence of pertussis-susceptible children aged ≥4 years who presented with acute respiratory infections.

Methods

This single-center, cross-sectional study conducted at the Paediatric Emergency Department from 1 October 2022, to 31 January 2023, included children aged 4 years and older with ARTIs symptoms and excluded those who were COVID-19 positive. B. pertussis was detected via quantitative Polymerase Chain Reaction on nasopharyngeal swabs and pertussis toxin (PT) IgG enzyme-linked immunosorbent assay.

Results

Children (n = 298) with a median (Interquartile range, [IQR]) age of 6

SUBMITTER: Binti Md Bahar AN 

PROVIDER: S-EPMC11892038 | biostudies-literature | 2024 Oct-Dec

REPOSITORIES: biostudies-literature