Clinical applications of immunoglobulin G against different individual <i>Aspergillus</i> species for the diagnosis of chronic pulmonary aspergillosis among at-risk populations.

ABSTRACT: Aspergillus fumigatus-specific IgG is often used as a diagnostic test for chronic pulmonary aspergillosis (CPA), but few studies have evaluated the performance and serology of IgGs from species other than A. fumigatus. In this study, we evaluated the serology and performance of different Aspergillus species-specific IgG antibodies in patients with CPA and at-risk populations and whether different Aspergillus species-specific IgGs could be of clinical utility and aid in the diagnosis of CPA caused by all Aspergillus species. A total of 187 participants were included between 2020 and 2022 (12 with CPA, 75 with old tuberculosis [TB], 45 with active TB and 55 with bronchiectasis). We measured the serum Aspergillus fumigatus, flavus, terreus, niger</

SUBMITTER: Keng LT 

PROVIDER: S-EPMC11892064 | biostudies-literature | 2024 Oct-Dec

REPOSITORIES: biostudies-literature