Epidemiology and risk factors of fungal pathogens in sepsis: a prospective nationwide multicenter cohort study.

ABSTRACT:

Background

The incidence of sepsis with identified fungal pathogens is increasing and is associated with higher morbidity and mortality. Co-infection with fungal infections in COVID-19 patients is attracting clinical attention. This study examines the epidemiology, risk factors, and outcomes among sepsis patients with identified fungal pathogens.

Methods

We conducted a nationwide cohort study of adult patients with sepsis from the Korean Sepsis Alliance Database in South Korea between September 2019 and December 2021. We identified 407 patients with documented fungal pathogens, categorized according to the presence of hemato-oncologic malignancies.

Results

Of the 11,981 patients with sepsis, fungal pathogens were identified in 3.4% of cases. Among these patients, 38.3

SUBMITTER: Lee JE 

PROVIDER: S-EPMC11892223 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature