Association between MASLD and increased risk of serious bacterial infections requiring hospital admission: A meta-analysis.

ABSTRACT:

Background

Previous studies have reported an association between metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of serious bacterial infections. However, the magnitude of the risk and whether this risk varies with the severity of MASLD remains uncertain. We performed a meta-analysis of observational studies to quantify the association between MASLD and serious bacterial infections requiring hospital admission.

Methods

We systematically searched PubMed, Scopus, Web of Science and Embase from database inception to 1 April 2024, using predefined keywords to identify studies examining the risk of serious bacterial infections among individuals with and without MASLD. MASLD was diagnosed using liver biopsy, imaging or International Classification of

SUBMITTER: Mantovani A 

PROVIDER: S-EPMC11892334 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature