Protective role of parenthood on age-related brain function in mid- to late-life.

ABSTRACT: The experience of human parenthood is near ubiquitous and can profoundly alter one's body, mind, and environment. However, we know very little about the long-term neural effects of parenthood for parents themselves, or the implications of pregnancy and caregiving experience on the aging adult brain. Here, we investigate the link between the number of children parented and age on brain function in 19,964 females and 17,607 males from the UK Biobank. In both females and males, parenthood was positively correlated with functional connectivity, such that higher number of children parented was associated with higher connectivity, particularly within the somato/motor network. Critically, the spatial topography of parenthood-linked effects was inversely correlated with the impact of age on functi

SUBMITTER: Orchard ER 

PROVIDER: S-EPMC11892684 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature