Diet, lifestyle and telomere length: using Copula Graphical Models on NHANES data.

ABSTRACT: Telomere length has been related to human health and ageing in multiple studies. However, these studies have analyzed a small set of variables, according to pre-formulated hypotheses. We used data from NHANES 1999-2002 to perform a preregistered cross-sectional analysis. From these four years we selected the participants with available leukocyte telomere length measure and with plausible daily energy intake, leading to a total study population of 7096 participants. Then, we divided the participants in three groups according to age: Young 20-39 (n = 2623), Middle 40-59 (n = 2210), Old 60-84 (n = 2263). On each group we performed Copula Graphical Modelling (CGM) to capture the links between the variables of interest, and we conducted certainty and sensitivity analyses to

SUBMITTER: Tedaldi AM 

PROVIDER: S-EPMC11892917 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature