Derivation of a CT Angiography-Based Arch Atherosclerosis Grading in Cryptogenic Ischemic Stroke.

ABSTRACT:

Background and objectives

We aimed to develop a novel computed tomography angiography (CTA)-based grading system to quantify the severity of aortic arch disease and compare the detection of aortic arch atherosclerosis (AAAthero) on routinely acquired arch-to-vertex CTA against transesophageal echocardiogram (TEE) among patients with cryptogenic ischemic stroke.

Methods

A systematic literature review was conducted to develop a computed tomography (CT)-based AAAthero grading system. CTA was compared against TEE for detecting AAAthero. The severity of arch atherosclerosis was scored based on a 5-point grading system. Patients with cryptogenic stroke who underwent both CTA and TEE were included in the derivation cohort to assess the sensitivity and specificity of CTA compared to

SUBMITTER: Wadhwa A 

PROVIDER: S-EPMC11892953 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature