Vibrio cholerae and Vibrio paracholerae bacteraemia strains encompass lineages that share resistome and virulome profiles.

ABSTRACT:

Background

Non-O1 and non-O139 Vibrio cholerae (NOVC) that cause bacteraemia have attracted the attention of the public health community around the world, mainly due to the prospect of outbreaks and the way to treat such infections.

Objectives

To identify V. cholerae lineages and their antibiotic resistance and virulence factors associated with bacteraemia.

Methods

Vibrio cholerae genomes associated with strains isolated from blood were retrieved and subjected to core genome-based phylogenomic analysis with Roary. The virulome and resistome were searched with abricate using the VFDB and CARD databases.

Findings

Analysis showed that, in addition to V. cholerae, Vibrio paracholerae also causes bacteraemia. The NOVC group was highly diverse, although genomes from

SUBMITTER: Morgado SM 

PROVIDER: S-EPMC11893007 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature