Dependence of brain-tissue R₂ on MRI field strength.

ABSTRACT:

Purpose

To quantify T₂ relaxation in the brain at 3 T and 7 T to study its field dependence and correlation with iron content, and to investigate whether iron can be separated from other sources of T₂ relaxation based on this field dependence.

Methods

Nine subjects were scanned at both field strengths with the same acquisition technique, which used multiple gradient-echo sampling of a spin echo. This allowed for separation of T₂ relaxation from static dephasing by B₀ field inhomogeneities and the effects of radiofrequency refocusing imperfections. The average relaxation rates (R₂ = 1/T₂) in multiple regions of interest in the brain were fitted with a model linear in B₀ and correlated with literature

SUBMITTER: van Gelderen P 

PROVIDER: S-EPMC11893036 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature