A patient with penile metastasis secondary to small cell lung cancer successfully treated with PD-1 inhibitors and chemotherapy: a case report and literature review.

ABSTRACT:

Background

Penile metastasis is an uncommon condition, with most primary malignancies originating in the abdominal cavity and pelvis. There have been very few reported cases originating from lung cancer, most of squamous cell carcinoma without small cell lung cancer.

Methods

We presented a case of penile metastasis secondary to small cell lung cancer, along with a review of relevant literature from the CNKI database.

Results

A 73-year-old male presented with a one-month history of palpable swelling in the penis without any chest symptoms. Beside penile lesion, PET/CT imaging also revealed a lesion in the left lobe of the lung, as well as multiple enlarged lymph nodes in the left hilum, mediastinum, and left supraclavicular fossa. Fiberoptic biopsy confirmed small cell

SUBMITTER: Zhang KC 

PROVIDER: S-EPMC11893422 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature