A thalamic hub-and-spoke network enables visual perception during action by coordinating visuomotor dynamics.

ABSTRACT: For accurate perception and motor control, an animal must distinguish between sensory experiences elicited by external stimuli and those elicited by its own actions. The diversity of behaviors and their complex influences on the senses make this distinction challenging. Here, we uncover an action-cue hub that coordinates motor commands with visual processing in the brain's first visual relay. We show that the ventral lateral geniculate nucleus (vLGN) acts as a corollary discharge center, integrating visual translational optic flow signals with motor copies from saccades, locomotion and pupil dynamics. The vLGN relays these signals to correct action-specific visual distortions and to refine perception, as shown for the superior colliculus and in a depth-estimation task. Simultaneously, brai

SUBMITTER: Vega-Zuniga T 

PROVIDER: S-EPMC11893466 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature