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Comparison of usability and user-friendliness of three FeNO analyzers in a general population cohort of the LEAD study.


ABSTRACT: Exhaled nitric oxide (FeNO) is a marker for airway inflammation measured by hand-held or stationary analyzers, but their usability was not previously assessed. NIOX VERO (CN), NObreath (BN), Vivatmo pro (BV), and CLD88 analyzer (reference, EC) were compared in a prospective study of the general population LEAD (Lung, hEart, sociAl, boDy) cohort, including the System Usability Scale and tests for equivalence at a clinically relevant range of ≤ 70 ppb with linear models and Bland-Altman plots. In 486 participants (62.4 ± 14.2 years old, 48.1% female), all hand-held analyzers had a good usability score, with BN scoring best. BV required the fewest attempts and time to measurement success, followed by BN. The FeNO results were clinically equivalent between devices (difference to EC 0.7-7.5 ppb

SUBMITTER: Idzko M 

PROVIDER: S-EPMC11893765 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature

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