Association between serum uric acid levels and bone mineral density in Chinese and American: a cross-sectional study.

ABSTRACT: Despite extensive studies conducted on the relationship between serum uric acid (UA) and bone mineral density (BMD), their association remains controversial. In this study, we investigated whether UA levels are independently associated with BMD in Chinese and American populations to elucidate their association. Herein, the data of 12,344 individuals (age > 20 years) from the National Health and Nutrition Examination Survey (2005-2018) and those of 768 individuals from the inpatient medical records and physical examination center systems of the Tertiary Class A Hospital (2021-2023) from China were included. The association between UA and BMD was analyzed by employing multivariate regression models with covariate adjustments. In addition, population description, stratified analysis, single-f

SUBMITTER: Li X 

PROVIDER: S-EPMC11894223 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature