Association between magnesium depletion score and Klotho levels among U.S. adults: Findings from NHANES 2007-2016.

ABSTRACT:

Background

Magnesium is a vital mineral that plays a crucial role in various physiological processes, and its imbalance has been associated with many chronic aging-related diseases. Traditional assessment methods are insufficient, and the Magnesium Depletion Score (MDS) has been proposed as a significant indicator. Klotho, a transmembrane protein, is involved in aging regulation and oxidative stress modulation. Despite the shared relevance of MDS and Klotho to aging, their relationship remains unclear.

Aims

This study aims to investigate the relationship between MDS and Klotho levels in U.S. adults.

Methods

We performed a cross-sectional analysis utilizing information from the NHANES database (2007-2016), including 8285 participants. MDS was computed according to spec

SUBMITTER: Ma X 

PROVIDER: S-EPMC11894308 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature