Developing an Indocyanine Green Angiography Protocol for Predicting Flap Necrosis During Breast Reconstruction.

ABSTRACT:

Background

Although there is evidence that indocyanine green angiography (ICGA) can predict mastectomy skin flap necrosis during breast reconstruction, consensus on optimal protocol is lacking. This study aimed to evaluate various technical factors which can influence ICG fluorescence intensity and thus interpretation of angiograms.

Method

Single institution retrospective study (2015-2021) of immediate implant-based breast reconstructions postmastectomy using a standardized technique of ICGA, controlling for modifiable factors of ambient lighting, camera distance and ICG dose. "Time to perfusion" assessment was defined as elapsed time from ICG administration to perfusion assessment. Intraoperative "absolute" and "relative" IGCA perfusion values of mastectomy flaps, taken at

SUBMITTER: Nguyen CL 

PROVIDER: S-EPMC11894893 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature