Changing Time Representation in Microsimulation Models.

ABSTRACT:

Background

In microsimulation models of diseases with an early, acute phase requiring short cycle lengths followed by a chronic phase, fixed short cycles may lead to computational inefficiency. Examples include epidemic or resource constraint models with early short cycles where long-term economic consequences are of interest for individuals surviving the epidemic or ultimately obtaining the resource. In this article, we demonstrate methods to improve efficiency in such scenarios. Furthermore, we show that care must be taken when applying these methods to epidemic or resource constraint models to avoid bias.

Methods

To demonstrate efficiency, we compared the model runtime among 3 versions of a microsimulation model: with short fixed cycles for all states (FCL), with dynamic

SUBMITTER: Wong EK 

PROVIDER: S-EPMC11894904 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature