A secure visualization platform for pathogenic genome analysis with an accurate reference database.

ABSTRACT: Investigating the genetic and developmental characteristics, infection transmission attributes, and epidemiological trends of pathogens using genomic data represents the foundation for pathogen surveillance and is a crucial prerequisite for guaranteeing global health security. To meet the analytical demands of research relating to pathogen prevention and control, we designed a secure visualization system capable of pathogen genome assembly, annotation, species identification, sequence typing, antibiotic resistance and virulence analysis, genomic mobile element and transferable resistance gene annotation, and phylogenetic tree reconstruction. For highly pathogenic organisms requiring complete data protection, we have developed a secure computing tool that utilizes a trusted execution enviro

SUBMITTER: Fan G 

PROVIDER: S-EPMC11894998 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature