Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes.

ABSTRACT:

Background

The triglyceride glucose index (TyG index) is a marker of insulin resistance linked to the incidence of major adverse cardiovascular events (MACE) in diverse populations. However, its long-term prognostic role in type 2 diabetes (T2D) remains underexplored. This study evaluated the predictive value of the TyG index for all-cause mortality and MACE in T2D over a period of more than 15 years.

Methods

A retrospective analysis was conducted on a cohort of 568 patients with T2D (median age: 67 years, IQR 61-72 years; 54% males; median disease duration: 14 years, IQR 7-21 years; median HbA1c: 7.3%, IQR 6.6-8.0%) and 376 presumably healthy controls (CTR, median age: 65 years, IQR 60-71 years) followed for a median period of 16.8 (IQR, 13.1-16.8) years. Routine biomarkers

SUBMITTER: Sbriscia M 

PROVIDER: S-EPMC11895143 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature