Comparison of high-flow nasal oxygen therapy and noninvasive ventilation in suspected sepsis patients with acute respiratory distress in the emergency department: a retrospective cohort study.

ABSTRACT:

Introduction

High-flow nasal cannula (HFNC) and non-invasive ventilation (NIV) are widely utilized respiratory support modalities for patients presenting with suspected sepsis and respiratory distress.This study aims to compare the 48-hour intubation rates between HFNC and NIV therapies in patients with suspected sepsis and respiratory distress.

Methods

This retrospective cohort study collected data over a 2-year period (January 2022 to December 2023) from patients presenting to the ED of Ramathibodi Hospital with suspected sepsis who received respiratory support with either HFNC or NIV. To analyze the incidence of intubation and 28-day mortality, we employed multivariable Cox regression to estimate hazard ratios (HRs). The hospital length of stay and ventilator-free days at

SUBMITTER: Angkoontassaneeyarat C 

PROVIDER: S-EPMC11895199 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature