Objectifying Clinical Outcomes After Lymphaticovenous Anastomosis and Vascularized Lymph Node Transfer in the Treatment of Extremity Lymphedema: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Upper extremity lymphedema (UEL) and lower extremity lymphedema (LEL) can develop as a result of lymph node dissection in the treatment of various malignancies. While emerging microsurgical interventions using lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) show promising outcomes for patients with lymphedema, the best approach to implementing the two procedures remains to be defined. This systematic review and meta-analysis provide a comprehensive overview of published literature on the clinical improvement of extremity lymphedema in patients who undergo either LVA, VLNT, or a combined microsurgical procedure.

Methods

From Embase, PubMed, and Web of Science databases, 52 studies were identified that met inclusion criteria. This revi

SUBMITTER: Hahn BA 

PROVIDER: S-EPMC11895410 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature